The last 30 years has seen unprecedented growth in global air travel. World air passenger demand was estimated at 2.45 billion passengers in 2009. With air traffic projected to double over the next 15-20 years, understanding the factors that influence passenger and flight crew health is of critical importance. For over a decade we have been conducting research related to aviation and health. We think of the airplane cabin as just another unique indoor environment where we can apply our building science and health science research.